BBC has the best coverage, it appears there are no survivors from the flight, and the death toll for civilians on the ground will be in multiples of 10. The video clip shows a Dreamliner struggling to gain altitude, slowly sinking into the village and producing a sharp nose-up shortly before crashing. The aircraft exploded on crashing, it appears the only major section left is the tail, stuck in the top of a building.
The aircraft crashed into a medical educational centre, with many medical trainees living in flats that have been seriously damaged and destroyed. Aircraft misconfiguration, crew mishandling of controls, high temperature on takeoff (it's reported it was over 40°C in the area when it took off), and also reports of the aircraft taking off a long way down the runway, meaning inadequate liftoff distance. The crew capabilities are going to come under examination, most surely.
https://www.bbc.com/news/live/c8d1r3m8z92t